✅Актуально в мае 2026 года
📋 О тесте
Test with answers on the topic «Vaccination against human papillomavirus prospects and evidence base»
Test with answers on the topic «Vaccination against human papillomavirus prospects and evidence base» разработан для специалистов, проходящих программы непрерывного медицинского образования (НМО). Число вопросов в тесте: 45 . Они охватывают ключевые аспекты темы.
Цель теста — проверить ваши знания и помочь закрепить материал, необходимый для успешной профессиональной деятельности. Каждый вопрос направлен на выявление глубины понимания теоретических и практических аспектов темы.
Успешное прохождение теста позволит вам:
- Повысить уровень профессиональных компетенций;
- Подтвердить соответствие стандартам НМО;
- Расширить свои знания в области медицины.
Пройдите тестирование прямо сейчас и убедитесь в своих знаниях!
Вопрос 1: Absolute contraindications to vaccination against the human papillomavirus are
- hypersensitivity to the components of the vaccine (верный ответ)
- postvaccinal complications of previous administration of the vaccine against papillomavirus infection (верный ответ)
- development of severe systemic allergic reactions (верный ответ)
- low-grade fever
Вопрос 2: Anogenital warts are a clinical manifestation of infection with the human papillomavirus of
- types 18 and 31
- types 33 and 39
- types 51 and 56
- types 6 and 11 (верный ответ)
Вопрос 3: In the Russian Federation, cervical cancer (CC) occupies
- the 1st place - in the structure of mortality among women of the most active and working age up to 45 years (верный ответ)
- the 2nd place in the prevalence of malignant neoplasms of the reproductive system (верный ответ)
- the 3rd place in the prevalence of all malignant neoplasms
- the 4th place in the number of years of life lost (верный ответ)
Вопрос 4: Currently, there are no methods for screening for HPV-associated oncological diseases:
- cancer of the anal canal (верный ответ)
- cancer of the vagina (верный ответ)
- vulvar cancer (верный ответ)
- cervical cancer
Вопрос 5: Regarding anal cancer, the following statements are true:
- the incidence of anal cancer in the general population is increasing among both men and women, especially in developed countries (верный ответ)
- the incidence of anal cancer is recorded much more often among HIV-infected people (верный ответ)
- HPV type 11 persistence can lead to more than 70% of anal cancer cases
- HPV type 16 persistence can lead to more than 70% of anal cancer cases (верный ответ)
Вопрос 6: Regarding anogenital warts, the following statements are true:
- Anogenital warts (AW) ais the most common clinical manifestation of high-risk human papillomavirus (HPV)
- anogenital warts (AW) is the most common clinical manifestation of low-risk oncogenic papillomaviruses (верный ответ)
- according to WHO, there are more than 42 million cases of anogenital warts worldwide every year (верный ответ)
- according to WHO, there are about 27 million cases of anogenital warts worldwide every year
Вопрос 7: Regarding vaccination against the human papillomavirus (HPV), the following statements are true:
- HPV vaccination eliminates the parallel possibility of vaccination against other infections
- the course of vaccination is recommended to be carried out before the beginning of sexual activity (верный ответ)
- the course of vaccination is recommended to be carried out after childbirth
- the main target group for vaccination should be girls from 9-10 years old to 13 years old (верный ответ)
Вопрос 8: Regarding vaccination against human papillomavirus and pregnancy are true statements:
- in case of vaccination carried out during pregnancy, it should be recommended to terminate this pregnancy
- if a woman becomes pregnant after the start of the vaccination series, the administration of the remaining dose should be postponed until the end of pregnancy (верный ответ)
- women who are planning a pregnancy should postpone vaccination until it is completed (верный ответ)
- women planning a pregnancy should be vaccinated according to a shortened scheme
Вопрос 9: Regarding immunization against the human papillomavirus in the puberty period, the following statements are true:
- the second dose is taken 2 months after the first dose
- if the second dose was taken earlier than 5 months after the first, the third dose should be taken necessarily (верный ответ)
- it is carried out according to a two-dose scheme (верный ответ)
- it is carried out according to the three-dose scheme
Вопрос 10: Regarding the methods of vaccination against the human papillomavirus (HPV), the following statements are true:
- after vaccination, the patient should be under the supervision of the doctor of the immunoprophylaxis office for 30 minutes or more (верный ответ)
- after vaccination, the patient should be under the supervision of the doctor of the immunoprophylaxis office for at least 15 minutes
- vaccinations should be carried out in the conditions of the immunoprophylaxis office
- vaccinations should be carried out in the conditions of the vaccination office (верный ответ)
Вопрос 11: Regarding human papillomavirus infection, the following statements are true:
- PVI is the cause of more than half of all cancers in women caused by infection (верный ответ)
- from 20 till 60 % of the sexually active population becomes infected during their lifetime
- from 70 till 80 % of the sexually active population becomes infected during their lifetime (верный ответ)
- the prevalence of papillomavirus infection (PVI) ranks first among sexually transmitted infections (верный ответ)
Вопрос 12: Regarding the duration of protection against papillomavirus infection in vaccinated patients, the following statements are true:
- protective antibody titers after a full course of vaccination with a tetravalent vaccine persist for up to 10 years (верный ответ)
- protective antibody titers after a full course of vaccination with a tetravalent vaccine persist for up to 5 years
- the antibody titer after the three-dose vaccination regimen remains stable for at least 15 years
- the antibody titer after the three-dose vaccination regimen remains stable for at least 5 years (верный ответ)
Вопрос 13: Regarding vulvar cancer, the following statements are true:
- in the structure of oncological pathology of malignant cancer of the vulva and vagina is about 3 to 7% (верный ответ)
- vulvar cancer is associated with the human papillomavirus (верный ответ)
- vulvar cancer is caused by a genetic predisposition
- most often, vulvar cancer develops in women 65-75 years old (верный ответ)
Вопрос 14: Regarding the quadrivalent papillomavirus vaccine the claims, the following statements are true:
- the vaccine is injected intradermally into the deltoid muscle of the shoulder
- the vaccine is injected intramuscularly into the deltoid muscle of the shoulder or the upper outer surface of the middle third of the thigh (верный ответ)
- the recommended course of vaccination is carried out according to the standard scheme, consisting of 3 doses (верный ответ)
- the recommended course of vaccination is carried out according to the standard scheme, consisting of 4 doses
Вопрос 15: Regarding the epidemiology of cervical cancer, the following statements are true:
- the incidence of breast cancer ranges from 1 to 50 cases per 100 thousand women (верный ответ)
- cervical cancer accounts for 84 % of cancers associated with the human papillomavirus (верный ответ)
- cervical cancer (CC) ranks 2nd in the world among all types of malignant neoplasms in women
- cervical cancer (CC) ranks 4th in the world among all types of malignant neoplasms in women (верный ответ)
Вопрос 16: Regarding the effectiveness of vaccines against human papillomavirus (HPV) , the following statements are true:
- The effectiveness of HPV vaccines can be assessed by reducing the incidence of cervical intraepithelial neoplasia CINI
- The effectiveness of HPV vaccines can be assessed by reducing the incidence of cervical intraepithelial neoplasia CINII-III (верный ответ)
- the effectiveness of vaccines in initially infected individuals is higher than in HPV-negative individuals
- The effectiveness of vaccines in initially uninfected individuals is higher than in HPV-positive individuals (верный ответ)
Вопрос 17: The leading mechanism of transmission of the human papillomavirus is
- airborne
- contact (верный ответ)
- vector-borne
- fecal-oral
Вопрос 18: The human papillomavirus (HPV) has a tropicity to epithelial cells of
- skin (верный ответ)
- mammary glands
- oral cavity (верный ответ)
- cervical mucosa (верный ответ)
Вопрос 19: What family does the human papillomavirus belong to?
- Ampullaviridae
- Papillomaviridae (верный ответ)
- Retroviridae
- Sphaerolipoviridae
Вопрос 20: Human papillomavirus types 16 and 18 cause cervical cancer
- in 10 % of cases
- in 23 % of cases
- in 60 % of cases
- in 70 % of cases (верный ответ)
Вопрос 21: Human papillomavirus is a group of common
- DNA-containing viruses that affect the epithelium of the skin and mucous membranes (верный ответ)
- DNA-containing viruses that affect the epithelium of the small intestine
- RNA-containing viruses affecting the endometrium
- RNA-containing viruses that affect the epithelium of the skin and mucous membranes
Вопрос 22: The bivalent vaccine provides protection against
- CIN II in the population of initially uninfected women – 54% (верный ответ)
- CIN II in the population of initially uninfected women – 65%
- CIN II у женщин, seronegative by 14 oncogenic types - 65% (верный ответ)
- CIN III у женщин, seronegative by 14 oncogenic types – more than 93% (верный ответ)
Вопрос 23: Bivalent recombinant vaccine against human papillomavirus (HPV) contains
- protein L1 of HPV type 16 (верный ответ)
- protein L1 of HPV type 18 (верный ответ)
- protein L1 of HPV type 31
- protein L1 of HPV type
Вопрос 24: For the primary specific prevention of diseases associated with papillomavirus infection, in the world are registered following vaccines:
- divalent (верный ответ)
- nine-valent (верный ответ)
- pentavalent
- quadrivalent (верный ответ)
Вопрос 25: To prevent the occurrence of cervical cancer, of paramount importance is
- usage of barrier methods of contraception
- examination sexual partners for the presence of sexual infections
- early detection and elimination of precancerous conditions (верный ответ)
- health education work on the ways of infection with the human papillomavirus
Вопрос 26: The protective effect of vaccination may be reduced due to
- a genetic defect (верный ответ)
- alcohol abuse
- receiving immunosuppressant therapy (верный ответ)
- taking oral contraceptives
Вопрос 27: Invasive cancer is preceded by precancerous lesions:
- intraepithelial neoplasia of the vagina (верный ответ)
- intraepithelial neoplasia of the vulva (верный ответ)
- leukoplakia of the cervix
- cervical intraepithelial neoplasia of the cervix (верный ответ)
Вопрос 28: Infect the epithelial layer of the urogenital tract can
- 10 types of human papillomavirus
- 15 types of human papillomavirus
- 25 types of human papillomavirus
- more than 30 types of human papillomavirus (верный ответ)
Вопрос 29: The most common post-vaccination complications of human papillomavirus vaccines include
- pain in the injection area (верный ответ)
- bronchospasm
- redness in the injection area (верный ответ)
- nausea
Вопрос 30: The types of viruses of high oncogenic risk include the human papillomavirus of
- 33 type (верный ответ)
- 39 type
- 45 type
- 51 type
Вопрос 31: The types of high-risk oncogenic viruses include
- 16 type (верный ответ)
- 18 type (верный ответ)
- 39 type (верный ответ)
- 43 type
Вопрос 32: The types of viruses of low oncogenic risk include the human papillomavirus of
- 11 type (верный ответ)
- 16 type
- 35 type
- 56 type
Вопрос 33: The types of low-risk oncogenic viruses include
- 16 type
- 18 type
- 42 type (верный ответ)
- 44 type (верный ответ)
Вопрос 34: Risk factors for the progression of cervical cancer include
- alcohol abuse
- smoking (верный ответ)
- concomitant sexually transmitted infections (верный ответ)
- the type of HPV and its oncogenic potential (верный ответ)
Вопрос 35: Mass vaccination of adolescents of both sexes is carried out
- in Australia (верный ответ)
- in New Zealand (верный ответ)
- in Russian Federation
- in USA (верный ответ)
Вопрос 36: The part of anal cancer caused by human papillomavirus types 16 and 18 accounts for
- 39 %
- 45 %
- 57 %
- 87 % (верный ответ)
Вопрос 37: The part of oropharyngeal cancer caused by human papillomavirus types 16 and 18 accounts for
- 19 %
- 33 %
- 71 %
- 89% (верный ответ)
Вопрос 38: The highest carcinogenic potentialthe has human papillomavirus of
- 16 type (верный ответ)
- 18 type
- 33 type
- 52 type
Вопрос 39: Low-oncogenic types of human papillomavirus are responsible for the development of vaginal cancer
- in 1,2 % of cases
- in 5,6 % of cases
- in 56 % of cases
- in 9,3% of cases (верный ответ)
Вопрос 40: Oropharyngeal cancer combines oncological diseases of several localizations of
- larynx (верный ответ)
- nasopharynx
- oral cavity (верный ответ)
- oropharynx (верный ответ)
Вопрос 41: The indication for the prescribing a tetravalent vaccine against the human papillomavirus is prevention among girls and women of
- anal cancer (верный ответ)
- vulvar cancer (верный ответ)
- cancer of the small intestine
- cervical cancer (верный ответ)
Вопрос 42: When conducting vaccination, it is necessary to be guided by
- instructions for the use of immunobiological drugs (верный ответ)
- national calendar of preventive vaccinations (верный ответ)
- regulatory documents on the organization of immunization (верный ответ)
- the results of meta-analyses in the area of vaccine prevention
Вопрос 43: The risk of transmission of the human papillomavirus with a single sexual contact is
- 10 %
- 30 %
- 50 %
- 80 % (верный ответ)
Вопрос 44: Types of human papillomavirus of high oncogenic risk cause the development of vulvar/vaginal cancer
- in 23 % of cases
- in 40 % of cases (верный ответ)
- in 50 % of cases
- in 90 % of cases
Вопрос 45: The factors contributing to infection with the human papillomavirus are
- barrier contraception
- immunodeficiency states (верный ответ)
- early onset of sexual activity (верный ответ)
- frequent change of sexual partners (верный ответ)
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